{"id":4110,"date":"2021-03-30T12:06:17","date_gmt":"2021-03-30T09:06:17","guid":{"rendered":"http:\/\/85.122.19.109\/?page_id=4110"},"modified":"2021-03-30T12:20:26","modified_gmt":"2021-03-30T09:20:26","slug":"prof-univ-dr-habil-marius-stefan","status":"publish","type":"page","link":"https:\/\/www.bio.uaic.ro\/?page_id=4110","title":{"rendered":"Prof. univ. dr. habil. Marius \u0218tefan"},"content":{"rendered":"\n
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Domenii de competen\u021b\u0103<\/span><\/h3>\n\n\n\n

Microbiologie general\u0103. Biotehnologii microbiene.<\/strong><\/span><\/strong>
UAIC, Corp B, Demisol I, B238-c
Tel: 0232\/201102 – int.1524<\/strong>
e-mail: stefanm@uaic.ro<\/a><\/p>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n

Teme de cercetare<\/span><\/h3>\n\n\n\n
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Noi molecule cu propriet\u0103\u021bi antimicrobiene<\/strong>.\u00a0<\/strong><\/strong><\/p>\n\n\n\n

Rezisten\u021ba la antibiotice a microorganismelor patogene este considerat\u0103 de Organiza\u021bia Mondial\u0103 a S\u0103n\u0103t\u0103\u021bii una din cele mai mari amenin\u021b\u0103ri la adresa s\u0103n\u0103t\u0103\u021bii omenirii. Din acest motiv, aten\u021bia cercet\u0103torilor este \u00eendreptat\u0103 spre identificarea de solu\u021bii alternative la utilizarea antibioticelor clasice care s\u0103 rezolve aceast\u0103 problem\u0103 global\u0103. Printre aceste solu\u021bii se num\u0103r\u0103 mai mul\u021bi compu\u0219i naturali (extracte de natur\u0103 vegetal\u0103, uleiuri volatile etc) sau artificiali (nanoparticule de argint, flavonoide de sintez\u0103) care sunt investiga\u021bi \u00een laboratorul nostru pentru identificarea propriet\u0103\u021bilor antibacteriene \u0219i antifungice. Studiile interdisciplinare au ca scop descrierea mecanismelor de ac\u021biune \u0219i identificarea aplica\u021biilor practice ale compu\u0219ilor investiga\u021bi.<\/p>\n\n\n\n

Interac\u021biuni plante-microorganisme la nivelul rizosferei<\/strong>.<\/strong><\/p>\n\n\n\n

Suprafe\u021bele r\u0103d\u0103cinilor plantelor reprezint\u0103 un mediu de via\u021b\u0103 preferat de numeroase popula\u021bii microbiene. Printre aceste microorganisme se num\u0103r\u0103 bacterii care pot influen\u021ba dezvoltarea plantelor folosind mecanisme diferite: cre\u0219terea disponibilit\u0103\u021bii unor nutrien\u021bi, stimularea dezvolt\u0103rii radiculare, protec\u021bia \u00eempotriva agen\u021bilor fitopatogeni. Studiile noastre vizeaz\u0103 izolarea \u0219i identificarea unor astfel de microorganisme care au proprietatea de a solubiliza fosforul anorganic, de a produce fitohormoni (acid 3-indolil acetic) sau molecule cu efect antifungic. Astfel de rizobacterii au o importan\u021b\u0103 practic\u0103 deosebit\u0103, put\u00e2nd fi utilizate ca biofertilizatori, biostimulatori \u0219i biopesticide \u00een agricultura organic\u0103.<\/p>\n\n\n\n

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Proiecte de cercetare<\/span><\/h3>\n\n\n\n
1. Contract PN III \u2013 CAPACIT\u0102\u021aI, Modulul III \u2013 Cooper\u0103ri Bilaterale, Romania – Africa de Sud, nr. 10BM\/2016 (2016-2017): Study of\u00a0Zea mays<\/em>\u00a0and\u00a0Vigna unguiculata<\/em>\u00a0rhizosphere diversity \u2013 premises for potential applications in bioeconomy.<\/strong><\/td><\/tr>
2. Contract PN II \u2013 CAPACIT\u0102\u021aI, Modulul III \u2013 Cooper\u0103ri Bilaterale Romania – Franta, nr. 780\/30.06.2014 (2015-2016): Aplica\u021bii ale unor biomolecule cu propriet\u0103\u021bi antifungice \u00een protec\u021bia plantelor.<\/strong><\/td><\/tr>
3. Contract PNCDI II – IDEI, nr. 249\/01.10.2007, cod CNCSIS 440 (2007-2010): Impactul unor tulpini rizobacteriene asupra proceselor de cre\u015ftere \u0219i dezvoltare la plante de soia (Glycine max<\/em>\u00a0L. Merr.).<\/strong><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Publica\u021bii<\/span><\/h3>\n\n\n\n
1. S\u00e2rbu, L.G., Bahrin, L.G., Babii, C.,\u00a0\u015etefan, M<\/strong>., Birsa, M.L., 2019 – Synthetic flavonoids with antimicrobial activity: a review<\/strong>, J. Appl. Microbiol., 1-9.<\/td><\/tr>
2. Babii, C., Mihalache, G., Bahrin, L.G., Neagu, A.N., Gostin, I., Mihai, M.C., Sarbu, L.G., Birsa, L.M.,\u00a0\u0218tefan, M<\/strong>., 2018 – A novel synthetic flavonoid with potent antibacterial properties: In vitro activity and proposed mode of action<\/strong>, PLOS ONE, 1-15.<\/td><\/tr>
3.\u00a0\u0218tefan, M<\/strong>., Munteanu, N., Stoleru, V., Mihasan, M., Hritcu, L., 2013 – Seed inoculation with plant growth promoting rhizobacteria enhances photosynthesis and yield of runner bean (Phaseolus coccineus<\/em>\u00a0L.)<\/strong>, Scientia Horticulturae, 151: 22-29.<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

Premii<\/span><\/h3>\n\n\n\n
Premiul\u00a0Grigore Antipa<\/em>\u00a0<\/strong>al Academiei Rom\u00e2ne, 2016, pentru lucrarea\u00a0Applied microbiology: from plant growth promotion to new neuroprotective drugs<\/em>.<\/strong><\/td><\/tr><\/tbody><\/table><\/figure>\n<\/div>\n\n\n\n
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R\u0103d\u0103cini de soia neinoculate (stg.) \u0219i inoculate (dr.) cu rizobacterii<\/em><\/em><\/figcaption><\/figure><\/div>\n<\/div>\n<\/div>\n\n\n\n

Studen\u021bi-doctoranzi<\/h3>\n\n\n\n
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Mihaela Savu<\/strong><\/span><\/h3>\n\n\n\n

e-mail:\u00a0mihaelasavu2@gmail.com<\/a><\/p>\n\n\n\n

Titlul tezei de doctorat<\/strong>: I-Cl flav \u2013 o nou\u0103 flavonoid\u0103 cu propriet\u0103\u0163i antimicrobiene.<\/p>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n

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Cristina-Veronica Moldovan<\/strong><\/span><\/h3>\n\n\n\n

e-mail:\u00a0mcristina.veronica@gmail.com<\/a><\/p>\n\n\n\n

Titlul tezei de doctorat<\/strong>: Studiul mecanismelor de rezisten\u0163\u0103 la antibiotice a microorganismelor. Flavonoide sintetice ca posibili agen\u0163i antimicrobieni.<\/p>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n

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Loredana-Elena Mantea<\/strong><\/span><\/h3>\n\n\n\n

e-mail:\u00a0mantealoredana9@gmail.com<\/a><\/p>\n\n\n\n

Titlul tezei de doctorat<\/strong>: Efectele stresului abiotic asupra solubiliz\u0103rii fosforului de c\u0103tre microorganismele rizosferice.<\/p>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

Domenii de competen\u021b\u0103 Microbiologie general\u0103. Biotehnologii microbiene.UAIC, Corp B, Demisol I, B238-cTel: 0232\/201102 – int.1524e-mail: stefanm@uaic.ro Teme de cercetare Noi molecule cu propriet\u0103\u021bi antimicrobiene.\u00a0 Rezisten\u021ba la antibiotice a microorganismelor patogene este considerat\u0103 de Organiza\u021bia Mondial\u0103 a S\u0103n\u0103t\u0103\u021bii una din cele mai mari amenin\u021b\u0103ri la adresa s\u0103n\u0103t\u0103\u021bii omenirii. Din acest motiv, aten\u021bia cercet\u0103torilor este \u00eendreptat\u0103 spre…
Cite\u0219te mai mult<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":1741,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-templates\/page-with-right-sidebar.php","meta":{"_editorskit_title_hidden":false,"_editorskit_reading_time":2,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}","_editorskit_typography_data":[],"_editorskit_blocks_typography":"","_uag_custom_page_level_css":"","footnotes":""},"class_list":["post-4110","page","type-page","status-publish","hentry"],"featured_image_src":null,"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false,"post-thumbnail":false,"mesmerize-full-hd":false},"uagb_author_info":{"display_name":"admin","author_link":"https:\/\/www.bio.uaic.ro\/?author=1"},"uagb_comment_info":0,"uagb_excerpt":"Domenii de competen\u021b\u0103 Microbiologie general\u0103. Biotehnologii microbiene.UAIC, Corp B, Demisol I, B238-cTel: 0232\/201102 – int.1524e-mail: stefanm@uaic.ro Teme de cercetare Noi molecule cu propriet\u0103\u021bi antimicrobiene.\u00a0 Rezisten\u021ba la antibiotice a microorganismelor patogene este considerat\u0103 de Organiza\u021bia Mondial\u0103 a S\u0103n\u0103t\u0103\u021bii una din cele mai mari amenin\u021b\u0103ri la adresa s\u0103n\u0103t\u0103\u021bii omenirii. Din acest motiv, aten\u021bia cercet\u0103torilor este \u00eendreptat\u0103 spre……","_links":{"self":[{"href":"https:\/\/www.bio.uaic.ro\/index.php?rest_route=\/wp\/v2\/pages\/4110","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.bio.uaic.ro\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.bio.uaic.ro\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.bio.uaic.ro\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bio.uaic.ro\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=4110"}],"version-history":[{"count":8,"href":"https:\/\/www.bio.uaic.ro\/index.php?rest_route=\/wp\/v2\/pages\/4110\/revisions"}],"predecessor-version":[{"id":4126,"href":"https:\/\/www.bio.uaic.ro\/index.php?rest_route=\/wp\/v2\/pages\/4110\/revisions\/4126"}],"up":[{"embeddable":true,"href":"https:\/\/www.bio.uaic.ro\/index.php?rest_route=\/wp\/v2\/pages\/1741"}],"wp:attachment":[{"href":"https:\/\/www.bio.uaic.ro\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=4110"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}