{"id":3686,"date":"2021-03-22T12:33:34","date_gmt":"2021-03-22T10:33:34","guid":{"rendered":"http:\/\/85.122.19.109\/?page_id=3686"},"modified":"2025-06-02T08:27:36","modified_gmt":"2025-06-02T05:27:36","slug":"cs-i-dr-habil-alin-ciobica","status":"publish","type":"page","link":"https:\/\/www.bio.uaic.ro\/?page_id=3686","title":{"rendered":"CS I dr. habil. Alin Ciob\u00eec\u0103"},"content":{"rendered":"
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Domenii de competen\u021b\u0103<\/span><\/h3>\n\n

Neurofiziologie animal\u0103. Comportament. Stres oxidativ<\/span>.<\/strong>
UAIC, Corp B, Demisol II, B130

e-mail: <\/a>alin.ciobica@uaic.ro<\/a><\/p><\/div><\/div><\/div><\/div><\/div><\/div>\n\n

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Teme de cercetare<\/span><\/h3>\n\n

Neurofiziologie animal\u0103. Comportament. Stres oxidativ..<\/strong><\/p>\n\n\n

Grupul nostru este interesat de \u00een\u0163elegerea modului \u00een care stresul oxidativ \u015fi principalii s\u0103i markeri din ser sau creier pot avea o valoare predictiv\u0103 \u00een evolu\u0163ia de la stadiile timpurii ale bolii neuropsihiatrice c\u0103tre faza patologic\u0103 acut\u0103, care este mult mai dificil de tratat. \u00cen plus, activitatea noastr\u0103 prive\u015fte utilizarea unor teste de natur\u0103 comportamental\u0103 \u015fi modele animale de boli neuropsihiatrice (boala Alzheimer, boala Parkinson, schizofrenie, anxietate, depresie, autism etc ) la \u015fobolan sau pe\u015ftii zebr\u0103. Acest lucru presupune modelarea unor disfunc\u0163ii de natur\u0103 comportamental\u0103 (\u00een cazul anxiet\u0103\u0163ii sau depresiei \u2013 testul labirintului plus ridicat sau testul de \u00eenot for\u0163at) sau chimic\u0103 din cadrul acestor boli (ex. administrarea de acid valproic \u00een cazul autismului sau de metionin\u0103 \u00een cazul schizofreniei). Toate aceste aspecte includ cercet\u0103ri de natur\u0103 neurofiziologic\u0103, histologic\u0103, biochimic\u0103 \u015fi molecular\u0103 referitoare la relevan\u0163a stresului oxidativ \u00een unele boli de natur\u0103 neuropsihiatric\u0103, studiate at\u00e2t la pacien\u0163i umani, c\u00e2t \u015fi la modele animale. Alte studii ale grupului privesc relevan\u0163a oxitocinei, a unor modific\u0103ri de natur\u0103 gastrointestinal\u0103 (sindromul de colon iritabil, microbiota etc), precum \u015fi influen\u0163a unor deficien\u0163e de natur\u0103 metabolic\u0103 \u015fi a exerci\u0163iilor fizice \u00een contextul bolilor neuropsihiatrice.<\/justify><\/p>\n\n\n

Proiecte de cercetare<\/span><\/h3>\n\n
1. PN-II-RU-TE-2014-4-1886, 2015-2017, Studiu complex privind relevan\u021ba administr\u0103rii de oxitocin\u0103 \u00een unele modele animale de boli neuropsihiatrice.\u00a0https:\/\/www.bio.uaic.ro\/cercetare\/contracte\/oxytocin\/prezentare.html<\/a><\/td><\/tr>
2. PN-II-RU-TE-2014-4-1886, 2015-2017, Studiu complex privind relevan\u021ba administr\u0103rii de oxitocin\u0103 \u00een unele modele animale de boli neuropsihiatrice.\u00a0https:\/\/www.bio.uaic.ro\/cercetare\/contracte\/oxytocin\/prezentare.html<\/a><\/td><\/tr><\/tbody><\/table><\/figure>\n\n

Publica\u021bii<\/span><\/h3>\n\n
1. P\u0103durariu, M.,\u00a0Ciobic\u0103, A<\/strong>., Hritcu, L.,\u00a0 Stoica, B., Bild, W., Stefanescu, C., 2010 – Changes of some oxidative stress markers in the serum of patients with mild cognitive impairment and Alzheimer’s disease, Neuroscience letters, 469 (1): 6-10.<\/td><\/tr>
2. P\u0103durariu, M.,\u00a0Ciobic\u0103, A<\/strong>., Dobrin, I., \u0218tef\u0103nescu, C., 2010 – Evaluation of antioxidant enzymes activities and lipid peroxidation in schizophrenic patients treated with typical and atypical antipsychotics, Neuroscience letters, 479 (3): 317-320.<\/td><\/tr><\/tbody><\/table><\/figure><\/div>\n\n\n\n
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Labirinte utilizate pentru teste comportamentale<\/em>.<\/figcaption><\/figure><\/div><\/div>\n<\/div>\n\n

Studen\u021bi-doctoranzi<\/h3>\n\n
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M\u0103d\u0103lina Andreea Robea<\/strong><\/span><\/h3>\n\n\n

e-mail:\u00a0madalina.robea11@gmail.com<\/a><\/p>\n\n\n\n

Titlul tezei de doctorat<\/strong>: Studii privind dezvoltarea \u0219i utilizarea pe\u0219telui zebr\u0103 ca model animal \u00een studierea tulbur\u0103rilor de spectru autist.<\/p>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n

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Roxana Cojocariu<\/strong><\/span><\/h3>\n\n\n

e-mail:\u00a0<\/a>roxana_20_2006@yahoo.com<\/a><\/p>\n\n\n\n

Titlul tezei de doctorat<\/strong>: Aspecte comportamentale, biochimice \u0219i genetice \u00een sindromul de colon iritabil – modele animale \u0219i pacien\u021bi umani.<\/p>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n

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Ilie Ovidiu-Dumitru<\/strong><\/span><\/h3>\n\n\n

e-mail:\u00a0<\/a>ovidiuilie13@gmail.com<\/a><\/p>\n\n\n\n

Titlul tezei de doctorat<\/strong>: Determinarea unor aspecte de biologie molecular\u0103 \u015fi relevan\u0163a microbiomului uman \u00een etiopatofiziologia bolii Parkinson.<\/p>\n<\/div>\n<\/div>\n\n\n

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Iuliana Simona Co\u0219man (c\u0103s. Luca)<\/strong><\/span><\/h3>\n\n\n

e-mail:\u00a0lucatinus2005@yahoo.com<\/a><\/p>\n\n\n\n

Titlul tezei de doctorat<\/strong>: Importan\u0163a func\u0163iei modulatoare a stresului oxidativ \u00een rela\u0163ia dintre boala Alzheimer \u015fi diabet (este boala Alzheimer un diabet de tip 3?).<\/p>\n<\/div>\n<\/div>\n\n\n

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Raluca Elena Du\u021b\u0103<\/strong><\/span><\/h3>\n\n\n

e-mail:\u00a0<\/a>duta.raluca112@gmail.com<\/a><\/p>\n\n\n\n

Titlul tezei de doctorat<\/strong>: Studiu complex privind implicarea vitdaminei D \u00een mecanismele fiziologice \u015fi biochimice ale unor manifest\u0103ri pshihiatrice asociate epilepsiei.<\/p>\n<\/div>\n<\/div>\n<\/div><\/div><\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"

Domenii de competen\u021b\u0103 Neurofiziologie animal\u0103. Comportament. Stres oxidativ.UAIC, Corp B, Demisol II, B130 e-mail: alin.ciobica@uaic.ro Teme de cercetare Neurofiziologie animal\u0103. Comportament. Stres oxidativ.. Grupul nostru este interesat de \u00een\u0163elegerea modului \u00een care stresul oxidativ \u015fi principalii s\u0103i markeri din ser sau creier pot avea o valoare predictiv\u0103 \u00een evolu\u0163ia de la stadiile timpurii ale bolii…
Cite\u0219te mai mult<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":1741,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-templates\/page-with-right-sidebar.php","meta":{"_editorskit_title_hidden":false,"_editorskit_reading_time":2,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}","_editorskit_typography_data":[],"_editorskit_blocks_typography":"","_uag_custom_page_level_css":"","footnotes":""},"class_list":["post-3686","page","type-page","status-publish","hentry"],"featured_image_src":null,"uagb_featured_image_src":{"full":false,"thumbnail":false,"medium":false,"medium_large":false,"large":false,"1536x1536":false,"2048x2048":false,"post-thumbnail":false,"mesmerize-full-hd":false},"uagb_author_info":{"display_name":"admin","author_link":"https:\/\/www.bio.uaic.ro\/?author=1"},"uagb_comment_info":0,"uagb_excerpt":"Domenii de competen\u021b\u0103 Neurofiziologie animal\u0103. Comportament. Stres oxidativ.UAIC, Corp B, Demisol II, B130 e-mail: alin.ciobica@uaic.ro Teme de cercetare Neurofiziologie animal\u0103. Comportament. Stres oxidativ.. Grupul nostru este interesat de \u00een\u0163elegerea modului \u00een care stresul oxidativ \u015fi principalii s\u0103i markeri din ser sau creier pot avea o valoare predictiv\u0103 \u00een evolu\u0163ia de la stadiile timpurii ale bolii……","_links":{"self":[{"href":"https:\/\/www.bio.uaic.ro\/index.php?rest_route=\/wp\/v2\/pages\/3686","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.bio.uaic.ro\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.bio.uaic.ro\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.bio.uaic.ro\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.bio.uaic.ro\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=3686"}],"version-history":[{"count":65,"href":"https:\/\/www.bio.uaic.ro\/index.php?rest_route=\/wp\/v2\/pages\/3686\/revisions"}],"predecessor-version":[{"id":22587,"href":"https:\/\/www.bio.uaic.ro\/index.php?rest_route=\/wp\/v2\/pages\/3686\/revisions\/22587"}],"up":[{"embeddable":true,"href":"https:\/\/www.bio.uaic.ro\/index.php?rest_route=\/wp\/v2\/pages\/1741"}],"wp:attachment":[{"href":"https:\/\/www.bio.uaic.ro\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=3686"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}